The epidemiology of chlamydia trachomatis organism load during genital infection: A systematic review

LA Vodstrcil; R McIver; WM Huston; SN Tabrizi; P Timms; JS Hocking

Journal article

The epidemiology of chlamydia trachomatis organism load during genital infection: A systematic review

LA Vodstrcil, R McIver, WM Huston, SN Tabrizi, P Timms, JS Hocking

Journal of Infectious Diseases | Published : 2015

DOI: 10.1093/infdis/jiu670

Abstract

Background. The role of organism load in Chlamydia trachomatis infection is not well understood. We conducted a systematic review to investigate the epidemiology of C. trachomatis organism load in human genital chlamydia infection. Methods. Embase, PubMed, and Medline databases were searched for literature published through August 2014. English-language publications that quantified load in humans were eligible. Participant characteristics and laboratory data were extracted. Results. A total of 737 records were identified, and 29 publications involving 40 883 participants were included. In women, load was highest for cervical swabs and lowest for urine specimens. In men, load was highest for ..

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University of Melbourne Researchers

Lenka Vodstrcil Author

Willa Huston Author

Jane Hocking Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (senior research fellowship APP1042907 to J. S. H. and project grant APP1023239 to J. S. H., W. M. H., S. N. T., P. T.).